Peptides for Weight Loss: Answering Your Top Questions

Peptide therapy is transforming medical weight loss, offering a personalized and science-backed approach with semaglutide and tirzepatide leading the way. These peptides for weight loss work by regulating physiological processes that influence appetite and metabolism, making it easier to manage weight. 

As with any treatment, questions may arise. And at Couture Med Spa, we’re here to provide the answers and personalized support you need on your journey to feeling your best.

What are Semaglutide/Tirzepatide Side Effects?

Semaglutide and tirzepatide are powerful weight loss tools, but they can cause mild side effects initially. The good news is that most symptoms resolve within a few weeks as your body adjusts. Plus, our expert providers are here with personalized tips to help you manage any mild symptoms and stay on track toward your goals.

How To Relieve Nausea From Semaglutide/Tirzepatide?

Some people may experience nausea on  with semaglutide or tirzepatide because these peptides slow digestion, helping regulate appetite and blood sugar. While this adjustment supports weight loss, it can temporarily upset your stomach. These strategies can ease discomfort:

Eat slowly: Take your time with your meals to avoid worsening nausea.

Avoid carb overload: Too many carbs can lead to water retention and an upset stomach.

Consider anti-nausea medication: Prescription options like Zofran may help ​if nausea persists so talk to your provider about these options.

Does Semaglutide Cause Constipation?

Yes, constipation is a possible side effect of semaglutide and tirzepatide as it slows digestion. But following these simple steps can help manage this symptom.

Increase fiber intake: Include fiber-rich foods like apples and broccoli in your diet.

Drink more water: Aim for at least half your body weight in ounces of water daily.

Try a gentle laxative: If necessary, start with Miralax once daily, increasing as needed. If constipation persists, consider adding Senna or Dulcolax at night.​

Why am I Gaining Weight on Semaglutide/Tirzepatide?

Weight gain on peptides is uncommon, but if it happens, it is often due to water retention from too many carbs or insufficient protein. If you notice the scale fluctuating:

Reassess your carb intake: Reducing high-carb foods like bread and rice can minimize water retention and help you stay on track

Prioritize protein: Protein supports muscle maintenance, which helps prevent weight gain by keeping your metabolism active and balanced.

Remember, weight management is a journey, and changes on the scale are a normal part of the process. Stay focused, celebrate your long-term progress, and trust the steps you’re taking to achieve your goals.

Does Semaglutide/Tirzepatide Cause Hair Loss​?

Hair loss is an uncommon side effect of semaglutide or tirzepatide, but it can happen, often due to rapid weight loss causing temporary stress on the body. To combat this:

Support hair health: Consider supplements like Nutrafol to strengthen hair and promote growth.

Maintain a balanced diet: Ensure you get enough protein and essential nutrients to support your overall health.

Do I Need to Exercise on Peptides for Weight Loss?

While exercise isn’t required for peptides to work, incorporating physical activity can boost your results and overall health. You don’t need to dedicate all your time to the gym—small, consistent movements go a long way.

Activities like walking, cycling, or swimming are excellent forms of cardio to help increase your metabolism. Strength training, such as weightlifting, is especially important for maintaining muscle mass, which supports a healthy metabolism. Aim for 150 minutes of activity per week, which can be spread out over 20-30 minutes a day to fit seamlessly into your routine. 

What Should I Eat On Semaglutide or Tirzepatide?

Some people may view semaglutide and tirzepatide as effective weight loss treatments that bypass diet, exercise, and portion control. However, the recommended peptide therapy diet for patients is similar to the general suggestions for a healthy diet. 

The ideal number of calories per day varies from person to person, depending on needs, size, and activity level. Some people may benefit from eating 1200 calories per day while others need closer to 2000 calories, but focusing on whole, nutrient-rich foods is the most essential part of maintaining a healthy lifestyle while reaching your weight goals. 

Some clean food examples include:

Lean Proteins: Chicken breasts, eggs and beans.

Vegetables: Leafy greens, mushrooms and zucchini.

Whole Grains: Brown rice, quinoa and millet.

Low- or Non-Fat Dairy: Milk, Greek yogurt and cottage cheese.

Fresh Fruits: Options like berries, apples and oranges (avoid dried fruits to minimize blood sugar spikes).

Avoid processed foods like white bread, pasta, and cereals, as they are packed with empty calories, refined sugars, and excess salt, leading to possible side effects. Instead, focus on including lean protein in every meal to help reduce blood sugar spikes and enhance feelings of fullness. An easy rule of thumb is to fill ¼ of your plate with protein and ½ with vegetables for a balanced, nutritious approach.

Still have questions about peptides for weight loss? Our team of experienced registered nurses is ready to provide the guidance you need during your free consultation. Let us help you take the first step toward feeling your best at Couture Med Spa.